The ANGPT2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to AGPT2, Angiopoietin 2, and ANGPT2. This antibody recognizes Human, Mouse, and Rat antigen. The ANGPT2 Antibody has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
ANGPT2 Antibody: Angiopoietin-2 (ANGPT2) is a member of the Ang family, a family of angiogenic factors that play major roles in angiogenesis during the development and growth of human cancers, but also during lymphangiogenesis. ANGPT2 is generally considered an antagonist of ANGPT1 and endothelial TEK tyrosine kinase (TIE-2, TEK). ANGPT2 disrupts the vascular remodeling ability of ANGPT1 and is thought to induce endothelial cell apoptosis, resulting in vessel regression. Expression of ANGPT2 has been linked to invasive and metastatic phenotypes of gliomas and other cancers